如你有此疾病,請遵照閣下醫生的完整醫療方案;而是否使用多學科復康方案前,你必須咨詢主診醫生的意見,如果閣下的主診醫生不建議您加入補充劑調理組合,請你不要使用。如果你需要尋求其他醫生作第二咨詢,閣下可聯絡我們線上<無邊界醫生>或你自己城市內的其他專業醫生的再診斷。
單純皰疹
單純皰疹病毒（HSV）1和2是普遍存在的病原體，持續感染者的生命。這些病毒產生終生感染的能力是由於在終末分化的神經元中存在一個潜伏的病毒池，最常見的是在外周神經節。據估計，全世界約90%的人感染了HSV-1、HSV-2或這兩種病毒（Arvin等人，2007年）。在美國，14-49歲人群中HSV-1和HSV-2的估計患病率分別為47.8%和11.9%，女性、墨西哥裔美國人和非西班牙裔黑人的患病率較高（McQuillan等人，2018）。單純皰疹病毒感染在臨床上通常是無症狀的。然而，HSV在一個稱為再啟動的過程中週期性地重新進入一個複製週期。在具有免疫能力的人中，再啟動事件會導致體表複製，從而導致反復出現水皰或潰瘍，這些水皰或潰瘍通常是自限性的，並且會迅速消失（Roizman等人，2013）。這些病變最常見於HSV-1感染的口腔、鼻腔或眼部，以及HSV-2感染的生殖器皮膚和粘膜。HSV再啟動也可導致免疫功能低下個體的顯著發病率和死亡率，在極少數情况下，中樞神經系統感染可導致急性病毒性腦炎或復發性淋巴細胞性腦膜炎。
HSV從潜伏期重新啟動並重新進入生產性複製週期的能力大大有助於其導致終生疾病的能力，從而導致反復感染、病毒脫落和向新宿主傳播。然而，潜伏期感染轉變為生產性感染的分子機制尚不清楚。
Ref: https://www.sciencedirect.com/science/article/pii/...
Herpes Simplex
Herpes simplex virus (HSV) 1 and 2 are ubiquitous pathogens that persist for the life of infected individuals. The ability of these viruses to develop lifelong infections is due to the presence of a latent pool of virus in terminally differentiated neurons, most commonly in the peripheral ganglia. It is estimated that approximately 90% of individuals worldwide are infected with HSV-1, HSV-2 or both of the viruses (Arvin et al., 2007). In the United States, the estimated prevalence rate of HSV-1 and HSV-2 in people aged 14–49 is 47.8% and 11.9% respectively, with higher prevalence in women and Mexican-American and non-Hispanic black persons (McQuillan et al., 2018). HSV infection is often clinically silent. However, HSV periodically re-enters a lytic replication cycle in a process known as reactivation. In immunocompetent persons, reactivation events result in replication at the body surface that can give rise to recurrent blisters or sores, which are typically self-limiting and resolve rapidly (Roizman et al., 2013). These lesions most commonly occur at oral, nasal or ocular sites with HSV-1 infection and at the genital skin and mucosa with HSV-2 infection. HSV reactivation can also lead to significant morbidity and mortality in immunocompromised individuals, and, in rare cases, infection of the central nervous system can lead to acute viral encephalitis or a recurrent lymphocytic meningitis.
The ability of HSV to reactivate from latency and re-enter a productive replication cycle significantly contributes to its ability to cause lifelong disease that results in recurrent infection, viral shedding and transmission to new hosts. However, the molecular events that underlie the switch from latent to productive infection are not well understood.
Ref: https://www.sciencedirect.com/science/article/pii/...
If you have this disease, please follow your doctor's complete medical plan. You must consult the attending doctor before using the multidisciplinary rehabilitation plan. If your attending doctor does not recommend you to join the supplement conditioning combination, please do not use it. If you need to seek second opinion from other doctors, you can contact our online "Doctors Without Borders", or another professional doctor in your own city.